Osteoporosis Profile II Test

Osteoporosis is a bone condition that causes reduced bone mass leading to frequent bone and joint pains, brittle bones and increased risk of fractures. Various factors apart from age, sex, and racial predisposition increase the risk of osteoporosis. The condition often goes undiagnosed till the occurrence of an injury, fracture or deformity. Hence, it is recommended to get an Osteoporosis Profile test to measure the various parameters in blood and urine that may increase the risk of osteoporosis in an individual. Even post diagnosis, these parameters are useful to assess the status of the disease. 

Osteoporosis is a disorder of the bones that results in less bone mass, brittle bones, and an increased likelihood of fractures. Besides age, sex, and ethnic predisposition, other factors also increase the probability of osteoporosis. Long-term use of some medicines, bad habits including smoking and drinking, hormonal imbalances, and menopausal problems, may lead to bone loss.

What is the Osteoporosis Profile II test?

The osteoporosis profile-II test examines the numerous blood and urine parameters that could raise a person's risk of developing osteoporosis. These factors can be used to evaluate the disease's status even after a diagnosis. The test measures the levels of:

1. calcium
2. alkaline phosphatase
3. parathyroid hormone (PTH)
4. deoxypyridinoline (DPD)
5. vitamin D
6. phosphorus
7. 25OH vitamin D2
8. osteocalcin
9. E2 levels in blood serum

It measures DPD levels, a biochemical marker of bone loss in a urine sample. This quick, non-invasive test aids in the early detection of osteoporosis. It also serves as a means of monitoring the effectiveness of hormone replacement therapy or mineral supplementation in treating the condition.

Written by: Dr.Shibani R, Medical Writer, Medical Affairs