Autoimmune Liver Disease Profile 4 Test

Reasons for Undergoing the Autoimmune Liver Disease Profile 4 Test

There are several reasons why your doctor may recommend the Autoimmune Liver Disease Profile 4 Test:

• Diagnosing Autoimmune Liver Diseases: If you are experiencing symptoms such as abdominal pain, jaundice, itchy skin, or fatigue, this test can help determine if an autoimmune liver disease is the underlying cause.
• Distinguishing Between Autoimmune Liver Conditions: The test helps differentiate between various autoimmune liver diseases, such as AIH and PBC, allowing for a more targeted treatment approach.
• Monitoring Disease Progression: If you have been diagnosed with an autoimmune liver disease, regular testing can help monitor the progression of the condition and assess the effectiveness of treatment.
• Ruling Out Other Liver Conditions: By identifying specific autoantibodies, the test can help rule out other liver conditions that may present with similar symptoms.

List of Parameters Considered During the Autoimmune Liver Disease Profile 4 Test

The Autoimmune Liver Disease Profile 4 Test measures several autoantibodies associated with specific autoimmune liver diseases:

• AMA M2: Indicates the presence of antimitochondrial antibodies, which are specific for primary biliary cholangitis (PBC).
• M2-3E (Bpo): Associated with the M2-3E isoform of PBC.
• Sp100: Indicates antibodies against the Sp100 protein, which are associated with PBC.
• PML: Indicates antibodies against the PML protein, which are associated with PBC.
• gp210: Indicates antibodies against the gp210 protein, which are associated with PBC.
• LKM1: Indicates the presence of anti-liver kidney microsomal antibodies type 1, which are associated with autoimmune hepatitis type 2 (AIH-2).
• LC1: Indicates the presence of antibodies against the LC1 protein, which are associated with AIH-2.
• SLA/LP: Indicates the presence of antibodies against the SLA/LP protein, which are associated with AIH.
• Ro52: Although not exclusively specific to liver diseases, it can be part of the autoimmune profile.

Autoimmune Liver Disease Profile 4 Test Preparation

To prepare for the Autoimmune Liver Disease Profile 4 Test, follow these steps:

• Fasting: A 12- to 14-hour fasting period is required before the test. Avoid eating or drinking anything except water during this time.
• Blood Sample Collection: A phlebotomist will collect a blood sample from a vein, usually in your arm. A tourniquet will be placed on your upper arm, and the skin will be disinfected before the needle is inserted.

Autoimmune Liver Disease Profile 4 Test Results & Interpretation

The results of the Autoimmune Liver Disease Profile 4 Test are interpreted based on the presence and levels of the autoantibodies:

• Positive Results: Indicate the presence of specific autoantibodies associated with autoimmune liver diseases. For example, positive AMA M2 suggests PBC, while positive LKM1 and LC1 indicate AIH type 2.
• Negative Results: Suggest the absence of these specific autoantibodies, but do not entirely rule out autoimmune liver diseases, as some tests can have false negatives.

Home Collection for Autoimmune Liver Disease Profile 4 Test Near You

Metropolis Healthcare offers a convenient home sample collection service for the Autoimmune Liver Disease Profile 4 Test. A trained phlebotomist will visit your residence to collect the blood sample, ensuring your comfort and safety while maintaining high standards of sample handling and testing accuracy. This service allows you to receive timely and reliable results without compromising on the quality of the diagnostic solution. By opting for Metropolis Healthcare's home collection option, you can benefit from their commitment to making healthcare accessible and providing quality diagnostic services conveniently at your doorstep.