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Testicular Marker Profile Test

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Testicular Marker Profile Test Overview

Testicular cancer is one of the commonly occurring cancers among males. Testicular cancer occurs due to formation of abnormal mass or growth around the testis or scrotum. The diagnosis or initial screening is done by certain cancer marker and some hormonal tests. Cancer markers or tumour markers are proteins produced by the normal cells as well as cancer cells, but are produced in higher levels by the cancer cells. Testicular Marker Profile consists of tests to measure the levels of tumour markers in the blood. This profile test is used along with other tests may be helpful in the diagnosis of testicular cancer and decide the treatment prognosis.

The testicular marker profile test, or testicular cancer test, is a vital diagnostic tool that measures the levels of specific tumour markers in the blood, namely human chorionic gonadotropin (HCG) beta and alpha-fetoprotein (AFP). These markers are proteins that are typically elevated in certain types of testicular cancer, especially in germ cell tumors, but may also be found in normal cells or other non-cancerous conditions. The test plays a crucial role in the diagnosis, monitoring, and prognosis of testicular cancer, helping healthcare professionals make informed decisions about patient care.

WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs

Reasons for Undergoing the Testicular Marker Profile Test

There are several reasons why a doctor may recommend undergoing the testicular cancer test:

  • Screening for Testicular Cancer: The test helps detect the presence of testicular cancer, especially in individuals experiencing symptoms such as abnormal lumps or masses around the testis, scrotal swelling or pain, or dull aching pain in the groin.
  • Monitoring Treatment: The testicular cancer blood test is used to monitor the effectiveness of treatment in patients diagnosed with testicular cancer, ensuring that the chosen therapy is yielding positive results.
  • Detecting Recurrence: After successful treatment, the test helps detect any recurrence of testicular cancer, allowing for timely intervention and management.
  • Prognostic Marker: The test results serve as a prognostic marker, helping determine the stage of cancer and assess the extent of metastasis, which is crucial for planning appropriate treatment strategies.
  • History of Cancer: Individuals with a history of cancer in other organs or a family history of testicular or prostate cancer may be advised to undergo the testicular cancer test as a precautionary measure.

List of Parameters Considered During the Testicular Marker Profile Test

The testicular cancer test focuses on two key tumour markers:

  • Human Chorionic Gonadotropin (HCG) Beta: Elevated levels of HCG Beta are associated with certain types of testicular cancers, particularly choriocarcinoma and non-seminomatous germ cell tumours. The presence of elevated HCG Beta levels can indicate the presence of these cancers.
  • Alpha-Fetoprotein (AFP): AFP levels are also elevated in certain types of testicular cancers, especially non-seminomatous germ cell tumours. Higher than normal AFP levels can suggest the presence of these cancers.

Testicular Marker Profile Test Preparation

Preparing for the testicular cancer test is straightforward, as it is a simple blood test that does not require any special preparation. No fasting is necessary before the test. However, it is important to follow any additional instructions provided by the healthcare provider or the laboratory to ensure accurate test results.

Testicular Marker Profile Test Results & Interpretation

The results of the testicular cancer test are interpreted based on the levels of HCG Beta and AFP:

  • Normal Range:
    • HCG Beta: 0 to 5 mIU/mL
    • AFP: up to 10 ng/mL
  • Elevated Levels: Any value above these normal ranges is considered elevated and may indicate the presence of testicular cancer or its recurrence. However, elevated levels of these markers can also be caused by other conditions, so further testing is necessary to confirm a diagnosis.

Home Collection for Testicular Marker Profile Test

Metropolis Healthcare offers a convenient home sample collection service for the testicular cancer test, providing comfort and safety for patients. A trained phlebotomist will visit your home to collect the blood sample, ensuring high standards of handling and accurate results. This service eliminates the need to visit a clinic or lab, saving time and effort. For those seeking a testicular cancer test online, Metropolis ensures timely and reliable results, empowering patients to take proactive steps in managing their health and improving outcomes. By enhancing healthcare accessibility, Metropolis Healthcare supports individuals on their path to better health.

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Testicular Marker Profile Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Testicular Marker Profile Test with a clear pricing structure.

The Testicular Marker Profile Test Price in Mumbai is ₹ 1,380 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Testicular Marker Profile measures the HCG Beta and AFP levels in the blood serum.

  • The test is useful for the screening of testicular cancer. The test should not be used in isolation but along with other specialized investigations and clinical correlation. 
  • For monitoring treatment and relapse in patients with testicular cancers.
  • The test may be used as a prognostic marker following cancer surgeries.
  • To know the stage of cancer as well as the metastasis status
  • The test can help detect recurrence, metastasis and residual cancer: This may even include patients with a history of cancer of other organs like prostate, lung etc.

People with the following symptoms which may be indicative of testicular cancers should undergo testing:

  • Abnormal lump or mass around the testis.
  • Scrotal swelling or pain.
  • Dull aching pain in the groin
  • Previous cancer history
  • Family history of prostate or testicular cancers.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

AFP-Alpha Feto Protein Test (AFP Test)

High AFP levels can be seen in hepatocellular carcinoma, non-seminomatous germ cell tumors and yolk sac tumors of the ovary. This test should not be used for diagnosis of cancer in isolation, as both false positive and negatives can occur.

HCG Beta Subunit Serum Test

High levels may occur in certain cases of testicular cancers.

False high or low levels may occur due to certain interferences by non-HCg substances.

AFP is normally made by a foetal liver and yolk sac. The test is done as part of cancer diagnosis to know the liver or pancreatic involvement due to cancer.

Human chorionic gonadotropin [HCG] is a hormone produced by the placenta mainly during pregnancy. In patients with cancer or undergoing treatment these levels may be helpful in the diagnosis of gestational trophoblastic disease (GTD), testicular tumors, ovarian germ cell tumors, teratomas, and, rarely, other human chorionic gonadotropin (hCG)-secreting tumors.

 

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